Immune

Thymosin Alpha-1

Approved in some countries; not Canada or USApproved drugTA1ThymalfasinZadaxin

A 28-amino-acid peptide from the thymus that helps regulate the immune system. As thymalfasin (Zadaxin) it's approved in dozens of countries, mostly in Asia, as an add-on for hepatitis B and C and some immune problems. It's not approved in Canada or the US.

Canada
Not authorized; seized by Health Canada in 2025
United States
Not approved (orphan designations only)

Download profile Opens in Vialchemy on your iPhone, where it's added to your Library as your own.

Not medical advice — talk to your doctor before making medical decisions.

At a glance

Class
Immune modulator
Mechanism
Supports T-cell function
Evidence
Approved abroad; clinical trials for hepatitis and other uses
Canada
Not authorized
Us
Not approved
Half Life
About 2 hours
Routes
SubQ
Common Side Effects
Site discomfort; generally well tolerated in trials
Key Cautions
Immune effects with autoimmune disease or transplant meds

What the research says

  • Is there real human evidence?

    More than most peptides here. It's approved as thymalfasin in many countries and studied in hepatitis, sepsis and as a vaccine add-on, with mixed results.

  • With autoimmune disease or immunosuppressants?

    It's designed to change immune activity. Anyone with autoimmune disease or on transplant or immune-suppressing medicine should talk to their doctor first.

Get medical care if

  • Redness, heat, swelling or pus at a site that spreads or comes with fever
  • Hives, swelling of the face or throat, or trouble breathing (call 911)

Buying and quality

  • Not authorized by Health Canada. Products sold online as "research use only" are illegal to sell for human use in Canada, and the label doesn't change that.
  • Health Canada warns these products may contain too much, too little or none of the peptide, plus contaminants like endotoxins, solvents, heavy metals or bacteria.
  • A certificate of analysis (COA) from the seller isn't independent proof. A 98% purity result still leaves 2% unidentified.
  • If you use it anyway: one clean needle per injection, sterile technique, label and date every vial, and stop if a site gets hot, red and spreading.

Dose calculator

Doses are set with your prescriber. This converts a dose you already have into what to draw; it doesn't recommend one. Check every number against your syringe and your vial's label.

Doses left in the vial
A blend vial

Not medical advice — talk to your doctor before making medical decisions.

Sources

Researched 2026-10-27. Trial results and approval status change.

  1. Health Canada: Unauthorized injectable peptides seized, Calgary (Apr 2025)
  2. PubMed: thymalfasin studies

General education, not medical advice. Nothing here is a dose recommendation. Doses, schedules and changes are set with a prescriber.